The iO Ultimate Clean Toothbrush Heads offer powerful yet gentle micro-vibrations with a unique dentist-inspired round brush head for a professional clean feeling every day. Designed exclusively for iO electric toothbrush handles, these Ultimate Clean brush heads help remove up to 100% more plaque than a regular manual toothbrush, leaving your teeth feeling clean and polished. The tufted bristles are precisely angled at 16 degrees to help clean hard-to-reach areas in your mouth. Dentists recommend replacing your brush head every 3 months for optimal results. The refill brush heads feature color-changing bristles that fade to white, signaling when it's time for a replacement. Experience superior cleaning power with the only refill brush heads designed exclusively for and guaranteed to fit your iO electric toothbrush. - Superior plaque removal: Perfectly angled brush head effectively yet gently removes up to 100% more plaque than a regular manual toothbrush along the gumline - Color-changing bristles: The refill brush heads have bristles that change color to signal when it's time to replace the brush head for maximum cleaning - Replace every 3 months: A worn brush head makes cleaning difficult and leaves bacterial plaque behind. For optimal cleaning, replace the brush head when the bristles fade to white - Exclusive for iO handles: Achieve superior cleaning power with the only brush head designed exclusively for and guaranteed to fit your iO electric toothbrush - Dentists' choice: The toothbrush brand most recommended by dentists worldwide